What are functional mushrooms and are they worth the hype?

What makes these mushrooms “functional”? Although the term might sometimes sound like a marketing slogan, it actually has a basis in science. In this introductory deep dive, explore what functional mushrooms are, how they work, and why they’re worth the hype. 

(TLDR: it’s all about the bioactive compounds).

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What makes a Mushroom Functional?

Imagine you eat a certain food and it not only gives you energy, but it also helps your body work better and/ or fight off diseases. This is the idea behind what makes a food “functional.” Although the term might sometimes sound like a marketing slogan, it actually has a basis in science. In this introductory deep dive, explore what functional mushrooms are, how they work, and why they’re worth the hype.

Functional Mushrooms: The Basics

Mushrooms are neither plant nor animal, but something else entirely —a kingdom of their own, filled with some unique compounds that have supported human health for centuries. Functional mushrooms aren’t the typical button mushrooms you toss on a pizza however, these ones are classified as functional because of their content of compounds which have health-supporting properties. These mushrooms can be delicious (like Shiitake or Lion’s Mane) and others too woody to eat (like Turkey Tail and Reishi)— but they all contain levels of specific naturally occurring antioxidants and substances that interact with the body in remarkable ways. These powerful health modulating compounds are considered “bioactive”. Think of them as small molecules that go beyond the nutrition in food and directly have an effect on the biology of the body.

Many functional mushrooms have been used for centuries in traditional medicine systems, like Chinese and Ayurvedic practices, so the prized classification of these mushrooms is nothing new. As I’m not one for simply anecdotal, possibly placebo or ‘woo woo’ish type medicines, I do admit I was guilty of brushing them off. However, I am so excited to see how modern research is now catching up, using new technologies and uncovering the science behind the benefits, from cognitive support to immune modulation.

For me, it was when I heard about the University of Queensland’s ground breaking work with Lion’s Mane that I realised just how new and exciting this science really is. Over just the last couple of years, their Queensland Brain Institute has been dedicated to researching the compounds and observing the effects of Lion’s Mane within the brain. In early 2023 UQ released a fascinating study showing that Lion’s Mane extract contains unique active components such as Hericinone A and NDPIH that stimulate the growth of new brain cells and improve memory in their mouse models. Using very high tech microscopes, the strengthening of neurons could actually be seen and measured! Listen to this podcast episode of UQ’s ‘A Grey Matter’ for more on how the study worked.

Besides Lion’s Mane, some of the other most well-known functional mushrooms and their bioactive components include:

  • Reishi (Ganoderma lucidum): Known as the "Mushroom of Immortality," it’s celebrated for stress relief and immune support. Bioactive compounds: triterpenoids (like ganoderic acids), polysaccharides (such as beta-glucans) and others.
  • Turkey Tail (Trametes versicolor): Packed with polysaccharides, this one’s a gut-health go-to for reducing inflammation and boosting your microbiome. Bioactive compounds: Polysaccharopeptides (PSP), Polysaccharide-K (PSK) and others.
  • Cordyceps (Cordyceps militaris): The performance enhancing mushroom that generates energy production by increasing ATP levels and improving oxygen utilization. Bioactive compounds: Adenosine, cordycepin and others.
Image from the 2023 UQ study illustrating the neuronal benefits Lion’s Mane. Read the published study in the Journal of Neurochemistry Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory

What Makes Them Functional?

As I touched on earlier, the power of functional mushrooms lies in their content of bioactive compounds. These are more than vitamins and minerals - these are molecules that are playing key roles in supporting biological processes. A couple quick examples:

  • Erinacines and Hericenones: These compounds have been studied for their ability to stimulate nerve growth factor (NGF), which plays a role in maintaining and regenerating neurons. Lion’s Mane is uniquely rich in these yet they are not found in any other plant or animal! Read a review.
  • Triterpenoids: Found in Reishi, these compounds contribute to its adaptogenic properties, helping the body handle stress and reducing inflammation by inhibiting inflammatory enzymes. Read the study.
Chemical structures of the Bioactive compounds in Lion's Mane Mushroom
Other examples of bioactive components reported in different edible mushrooms. (Click for source link)

Why Are They Gaining Popularity Now?

Functional mushrooms aren’t new—humans have been using them for thousands of years. But as modern wellness trends shift toward natural and holistic health solutions, these fungi are becoming increasingly popular because their effects on health are finally being studied, measured and the results have real exciting potential!

Now people of all backgrounds, ages and wellness goals are turning to functional mushrooms for:

  • Cognitive Support: Lion’s Mane is a favourite for its demonstrated potential to enhance focus and memory. Check out a study.
  • Immune Boosting: Turkey Tail’s polysaccharides, such as Polysaccharide K (PSK) and Polysaccharopeptide (PSP), have shown an immunoregulatory effect and support the body’s ability to suppress tumours. Read a review.
  • Stress Management: Reishi is widely considered an adaptogen, which helps the body adapt to stress by modulating cortisol levels and supporting adrenal function. Its bioactive compounds, such as triterpenes and polysaccharides, contribute to these effects. Check out a study.

As I’ve said, what makes this particularly exciting is the growing body of scientific research. While traditional use provides a strong foundation, my point is that it’s the lab-based evidence that is helping mushrooms move from traditional lore to mainstream health.

Edible mushrooms, bioactive components, and health benefits. (Click for source link)

How to Incorporate Functional Mushrooms

Functional mushrooms are versatile. You can find them as powders, tinctures, capsules, or even infused into tea or coffee. It’s all about finding what fits your lifestyle and what your individual goals are. I’m not here to yuck anyone’s yum or tell you there’s no place for anyone else’s product. It’s about what works for you.

For example, adding a gram of Lion’s Mane powder to your morning coffee is an easy and economical way to get your serve of beta-glucans. Or perhaps a Reishi tincture is the indispensable item you pack when travelling to help manage jet lag. Maybe you’re concerned with an aging parent’s health overall so a combination of mushrooms is what they’ll be getting because they’re needing every drop.

Dual - Extracts have a measured dropper making a 1ml serve easy to measure.
These extracts are a full spectrum product meaning that the bioactive compounds that dissolve in water PLUS the bioactive compounds that do not dissolve in water are taken out of the mushroom in separate precise steps, making the mushroom’s active ingredients far more concentrated and easier for your body to absorb.

My Take

As someone who handles mushrooms daily I’ve seen firsthand how these incredible fungi can support wellness. I will tell you my own personal stories with these, including my first experience with a mushroom extract, on a later day. I’m also all about transparency, so while functional mushrooms won’t make you invincible or like the movie “Limitless”, they can be a helpful part of a balanced, health-conscious lifestyle with tangible benefits.

At MYCOfactor, I’m committed to creating products that deliver the best of what these mushrooms have to offer. It’s about science, quality, and sharing the real benefits of these functional fungi with you.

So, whether you’re a seasoned mushroom lover or perhaps just curious, functional mushrooms are worth exploring and I’m excited to help you discover all they can do.

Warmly,
Rachel
Founder of MYCOfactor