Mushrooms are neither plant nor animal, but something else entirely —a kingdom of their own, filled with some unique compounds that have supported human health for centuries. Functional mushrooms aren’t the typical button mushrooms you toss on a pizza however, these ones are classified as functional because of their content of compounds which have health-supporting properties. These mushrooms can be delicious (like Shiitake or Lion’s Mane) and others too woody to eat (like Turkey Tail and Reishi)— but they all contain levels of specific naturally occurring antioxidants and substances that interact with the body in remarkable ways. These powerful health modulating compounds are considered “bioactive”. Think of them as small molecules that go beyond the nutrition in food and directly have an effect on the biology of the body.
Many functional mushrooms have been used for centuries in traditional medicine systems, like Chinese and Ayurvedic practices, so the prized classification of these mushrooms is nothing new. As I’m not one for simply anecdotal, possibly placebo or ‘woo woo’ish type medicines, I do admit I was guilty of brushing them off. However, I am so excited to see how modern research is now catching up, using new technologies and uncovering the science behind the benefits, from cognitive support to immune modulation.
For me, it was when I heard about the University of Queensland’s ground breaking work with Lion’s Mane that I realised just how new and exciting this science really is. Over just the last couple of years, their Queensland Brain Institute has been dedicated to researching the compounds and observing the effects of Lion’s Mane within the brain. In early 2023 UQ released a fascinating study showing that Lion’s Mane extract contains unique active components such as Hericinone A and NDPIH that stimulate the growth of new brain cells and improve memory in their mouse models. Using very high tech microscopes, the strengthening of neurons could actually be seen and measured! Listen to this podcast episode of UQ’s ‘A Grey Matter’ for more on how the study worked.
Besides Lion’s Mane, some of the other most well-known functional mushrooms and their bioactive components include:
- Reishi (Ganoderma lucidum): Known as the "Mushroom of Immortality," it’s celebrated for stress relief and immune support. Bioactive compounds: triterpenoids (like ganoderic acids), polysaccharides (such as beta-glucans) and others.
- Turkey Tail (Trametes versicolor): Packed with polysaccharides, this one’s a gut-health go-to for reducing inflammation and boosting your microbiome. Bioactive compounds: Polysaccharopeptides (PSP), Polysaccharide-K (PSK) and others.
- Cordyceps (Cordyceps militaris): The performance enhancing mushroom that generates energy production by increasing ATP levels and improving oxygen utilization. Bioactive compounds: Adenosine, cordycepin and others.
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